MTHFR Research

Section A1: MTHFR C677T Mutations

Hypertension in Homozygous C677T MTHFR Individuals: Reduction in Systolic and Diastolic Blood Pressure using RiboflavinDown’s Syndrome Etiology Linked to Mothers with MTHFR C677T PolymorphismsDown’s Syndrome Etiology Linked to Mothers with MTHFR C667T, MTHFR A1298C, MTR and RFCIMethotrexate Toxicity in Individuals with C677T MTHFR PolymorphismsBreast Cancer Risk with BRCA Mutation Combined with MTHFR C677T and/or MTR A2756G Variants: Weak TrendDeep Venous Thrombosis in Post-Operative Individuals with Homozygous C677T MTHFR PolymorphismsColon Cancer Risk Increase with Homozygous C677T PolymorphismsColon Cancer Risk Reduction in those with Homozygous C677T when supplemented with methyl donors.Nitrous Oxide Increases Homocysteine Significantly in those with Homozygous C677T MTHFR MutationsAtrial Fibrillation Risk Increases with MTHFR C677T MTHFR Mutation and Elevated Homocysteine LevelsEpilepsy: Prevalence of Homozygous MTHFR C677T MTHFR MutationsInfertility in MTHFR-Deficient Male Mice Is Partially Alleviated by Lifetime Dietary Betaine SupplementationPeripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysisMigraines and C677T MTHFR

Section B: MTHFR A1298C Mutations

ADHD in A1298C MTHFR Polymorphisms: Possible RelationshipInfertility in Homozygous A1298C MTHFR Polymorphisms: Idiopathic Indian Male InfertilityRheumatoid Arthritis + MTHFR A1298C Polymorphisms Predispose Individuals to Increased Cardiovascular RiskTurner Syndrome and Homozygous A1298C Polymorphisms: LinkedElevated Homocysteine in Homozygous A1298C MTHFR Polymorphisms: Indirect Finding (page 38)

Section C: Compound Heterozygous MTHFR Mutations

Congential Heart Disease and Compound Heterozygous MTHFR Mothers: Increase in Newborns with Congential Heart DiseaseDeep Venous Thrombosis Risk in Post-Operative Individuals: Increased Risk in Compound Heterozygous MTHFR IndividualsMeningioma and Glioma Incidence Associated with MTHFR Compound Heterozgyous Polymorphisms (and in MTRR 66G)Association of Polymorphisms in One-Carbon Metabolism Genes and Postmenopausal Breast Cancer Incidence