• Dr. Amber Brooks

MTHFR Research

MTHFR Mutation Research Articles

Section A1: MTHFR C677T Mutations

Hypertension in Homozygous C677T MTHFR Individuals: Reduction in Systolic and Diastolic Blood Pressure using RiboflavinDown’s Syndrome Etiology Linked to Mothers with MTHFR C677T PolymorphismsDown’s Syndrome Etiology Linked to Mothers with MTHFR C667T, MTHFR A1298C, MTR and RFCIMethotrexate Toxicity in Individuals with C677T MTHFR PolymorphismsBreast Cancer Risk with BRCA Mutation Combined with MTHFR C677T and/or MTR A2756G Variants: Weak TrendDeep Venous Thrombosis in Post-Operative Individuals with Homozygous C677T MTHFR PolymorphismsColon Cancer Risk Increase with Homozygous C677T PolymorphismsColon Cancer Risk Reduction in those with Homozygous C677T when supplemented with methyl donors.Nitrous Oxide Increases Homocysteine Significantly in those with Homozygous C677T MTHFR MutationsAtrial Fibrillation Risk Increases with MTHFR C677T MTHFR Mutation and Elevated Homocysteine LevelsEpilepsy: Prevalence of Homozygous MTHFR C677T MTHFR MutationsInfertility in MTHFR-Deficient Male Mice Is Partially Alleviated by Lifetime Dietary Betaine SupplementationPeripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysisMigraines and C677T MTHFR

Section B: MTHFR A1298C Mutations

ADHD in A1298C MTHFR Polymorphisms: Possible RelationshipInfertility in Homozygous A1298C MTHFR Polymorphisms: Idiopathic Indian Male InfertilityRheumatoid Arthritis + MTHFR A1298C Polymorphisms Predispose Individuals to Increased Cardiovascular RiskTurner Syndrome and Homozygous A1298C Polymorphisms: LinkedElevated Homocysteine in Homozygous A1298C MTHFR Polymorphisms: Indirect Finding (page 38)

Section C: Compound Heterozygous MTHFR Mutations

Congential Heart Disease and Compound Heterozygous MTHFR Mothers: Increase in Newborns with Congential Heart DiseaseDeep Venous Thrombosis Risk in Post-Operative Individuals: Increased Risk in Compound Heterozygous MTHFR IndividualsMeningioma and Glioma Incidence Associated with MTHFR Compound Heterozgyous Polymorphisms (and in MTRR 66G)Association of Polymorphisms in One-Carbon Metabolism Genes and Postmenopausal Breast Cancer Incidence


Dr. Amber Brooks FNP, CACCP, BCIP, DC is a pediatric expert bridging alternative and traditional

medicine by providing individualized and comprehensive approaches to pediatric wellness. Her experience is unique, as she is Board Certified in Integrative Pediatrics, Board Certified as a Pediatric Chiropractor, a Family Nurse Practitioner and Craniosacral Therapist.

Dr. Brooks FNP, CACCP, BCIP, DC has been extremely successful in assisting her patients in achieving optimal health and wellness by using the best integrative methods to help support their growing bodies. She provides traditional and alternative medicine for maximal health. Dr. Brooks has developed specialized methods to answer today's biggest pediatric health problems including allergies, constipation, chronic ear infections, birth trauma, developmental delays, digestive problems, Autism, ADD/ADHD, MTHFR, nutritional, and behavioral problems.

Dr. Amber Brooks FNP, CACCP, BCIP, DC has extensive experience solving complex pediatric and unique perspective of diagnosing the problem rather than treating the symptoms has led to 

remarkable results worldwide. Parents praise her current, yet practical, guidance to what a child is struggling with and tools to help the family improve their child's future health.

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Dr. Amber Brooks, DC, MSN, CACCP, BCIP, RN Does Not Provide Medical Advice, Diagnosis Or Treatment. Content Throughout The Site Is For Informational Purposes Only And Is Not Intended To Be A Substitute For Professional Medical Care Or Diagnosis. Please Seek The Advice Of Your Primary Physician Or Other Qualified Health Provider With Any Questions You May Have Regarding Your Medical Condition. The Views And Statements Expressed On The Site (Film/Media/Testimonials/Blogs/Etc) Do Not Necessarily Reflect The Views Of Whole Child Wellness Or Amber Brooks, DC, MSN, CACCP, BCIP, RN. Whole Child Wellness, Amber Brooks, DC, MSN, CACCP, BCIP, RN, And Any Other Person Involved In The Making And Distribution Of The Material Do Not Warrant The Accuracy, Reliability, Currency, Or Completeness Of Those Views Or Statements And Do Not Accept Any Legal Liability Whatsoever Arising From Any Reliance On The Views, Statements, And Subject Matter Of The Material. The Material, The Views And Statements Expressed In The Film/Media/Testimonials/Site Are Not Substitutes For Independent Professional Medical Advice. Viewers Should Exercise Their Own Care, Skill And Diligence With Respect To The Reliance And Use Of Any Information Contained In The Site. Viewers Should Not Act Or Refrain From Acting On The Basis Of The Views And Statements Expressed In The Content Without First Seeking Appropriate Professional Medical Advice With Respect To Their Own Particular Circumstances.